CBJ: Business Briefcase

l Advanced Technologies Home Care Inc., the largest privately held home health care agency in Virginia, has been designated as one of the 2008 HomeCare Elite, a compilation of the top 25 percent most successful home health care agencies in the country. AT Home Care is a Richmond-based company with an office in Charlottesville. This is the fourth consecutive year the company has attained the ranking.

l Tau Therapeutics LLC of Charlottesville has been granted orphan drug status by the U.S. Food and Drug Administration to its leading drug candidate, mibefradil, for the treatment of pancreatic cancer. The Orphan Drug Act of 1983 allows the FDA to grant special status to companies treating diseases afflicting fewer than 200,000 Americans that gives them seven years of market exclusivity in addition to other regulatory assistance and benefits. Tau is a development stage biopharmaceutical company built on a revolutionary means of inhibiting the growth of cancer cells.